Recent Publications

Singh, V., Basu, A., Shivapriya, P., Varadwaj, P. K., Samanta, S. K., & Sahoo, A. K. (2019). Exploration of interactions of “blood-nano interface” of carbon-based nanomaterials for biomedical applications. Journal of Materials Research, 34(11), 1950–1964.
Aier, I., & Varadwaj, P. K. (2019). Understanding the Mechanism of Cell Death in Gemcitabine Resistant Pancreatic Ductal Adenocarcinoma: A Systems Biology Approach. Current Genomics, 20(7), 483–490.
Roy, N., Raj, U., Rai, S., & Varadwaj, P. K. (2019). Deciphering the Novel Target Genes Involved in the Epigenetics of Hepatocellular Carcinoma Using Graph Theory Approach. Current Genomics, 20(8), 545–555.
Aier, I., Semwal, R., Dhara, A., Sen, N., & Varadwaj, P. K. (2019). An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma. PloS One, 14(10).
Yadav, T. C., Agarwal, V., Srivastava, A. K., Raghuwanshi, N., Varadwaj, P., Prasad, R., & Pruthi, V. (2019). Insight into Structure-Function Relationships of β-Lactamase and BLIPs Interface Plasticity using Protein-Protein Interactions. Current Pharmaceutical Design, 25(31), 3378–3389.
Mishra, V. K., Gupta, S., Chand, R., Yadav, P. S., Singh, S. K., Joshi, A. K., & Varadwaj, P. K. (2019). Comparative transcriptomic profiling of High-and Low-grain Zinc and Iron containing Indian wheat genotypes. Current Plant Biology, 18, 100105.
Semwal, R., Aier, I., Varadwaj, P. K., & Antsiperov, S. (2019). PROcket, an Efficient Algorithm to Predict Protein Ligand Binding Site. In International Work-Conference on Bioinformatics and Biomedical Engineering (pp. 453–461). Springer, Cham.
Yadav TC, P. V., Kumar N, Raj U, Goel N, Vardawaj PK, Prasad R. (2019). Exploration of interaction mechanism of tyrosol as a potent anti-inflammatory agent. J Biomol Struct Dyn., 1–16.
Mishra, V. K., Gupta, S., Chand, R., Yadav, P. S., Singh, S. K., Joshi, A. K., & Varadwaj, P. K. (2019). Unveiling the transcriptome complexity of the High-and Low-Zinc & Iron accumulating Indian wheat (Triticum aestivum L.) cultivars. BioRxiv, 538819.
Aier, I., Semwal, R., Sharma, A., & Varadwaj, P. K. (2019). A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer. Cancer Epidemiology, 58, 104–110.
Raghuwanshi, N., Yadav, T. C., Srivastava, A. K., Raj, U., Varadwaj, P., & Pruthi, V. (2019). Structure-based drug designing and identification of Woodfordia fruticosa inhibitors targeted against heat shock protein (HSP70-1) as suppressor for Imiquimod-induced psoriasis like skin inflammation in mice model. Materials Science and Engineering: C, 95, 57–71.
Kumar, A., Mehta, V., Raj, U., Varadwaj, P. K., Udayabanu, M., Yennamalli, R. M., & Singh, T. R. (2019). Computational and in-vitro validation of natural molecules as potential Acetylcholinesterase inhibitors and neuroprotective agents. Current Alzheimer Research, 16(2), 116–127.
Sharma, A., Kumar, R., Aier, I., Semwal, R., Tyagi, P., & Varadwaj, P. (2019). Sense of smell: Structural, functional, mechanistic advancements and challenges in human olfactory research. Current Neuropharmacology, 17(9), 891–911.
Gupta, S., Mishra, V. K., Kumari, S., Chand, R., Varadwaj, P. K., & others. (2019). Deciphering genome-wide WRKY gene family of Triticum aestivum L. and their functional role in response to Abiotic stress. Genes & Genomics, 41(1), 79–94.
Kumar, N., Gupta, S., Chand Yadav, T., Pruthi, V., Kumar Varadwaj, P., & Goel, N. (2019). Extrapolation of phenolic compounds as multi-target agents against cancer and inflammation. Journal of Biomolecular Structure and Dynamics, 37(9), 2355–2369.

Raj, U., Mishra, S. K., Bhatia, C., Varadwaj, P. K., & Harit, G. (2018). A Comprehensive Knowledgebase on Cancer Epigenetics. In 2018 International Conference on Bioinformatics and Systems Biology (BSB) (pp. 198–202). IEEE.
Geraldo, J. A., Silva, F., Horacio, E. C., Leao, A., Brayan, A., Fernandes, G., … others. (2018). Highlights of the 2nd Brazilian student council symposium, organized by ISCB Regional Student Group Brazil. PeerJ PrePrints.
Gupta S, V. P., Singh Y, Kumar H, Raj U, Rao AR. (2018). Identification of Novel Abiotic Stress Proteins in Triticum aestivum Through Functional Annotation of Hypothetical Proteins. Interdiscip Sci., 10(1), 205–220.
Mishra S, M. K., Kumar A, Varadwaj PK. (2018). Structure-Based Drug Designing and Simulation Studies for Finding Novel Inhibitors of Heat Shock Protein (HSP70) as Suppressors for Psoriasis. Interdiscip Sci., 10(2), 271–281.
Mishra, P., S. .. Aier, I. .. Varadwaj. (2018). Integrated Pathways of Candida albicans Revealing Potential Targets and Key Factors Accountable for Pathogenicity. Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci., 8(31), 1–10.
Mondal, M., Semwal, R., Raj, U., Aier, I., & Varadwaj, P. K. (2018). An entropy-based classification of breast cancerous genes using microarray data. Neural Computing and Applications, 1–8.
Jain, B., Raj, U., Varadwaj, P. K., & Alladi, S. M. (2018). CADD approaches to counter Tuberculosis. Current Topics in Medicinal Chemistry, 18(13), 1031.
Rai, S., Raj, U., & Varadwaj, P. K. (2018). Systems biology: a powerful tool for drug development. Current Topics in Medicinal Chemistry, 18(20), 1745–1754.
Kumar, P., Raj, U., Aier, I., & Varadwaj, P. K. (2018). Decoding methylation patterns in ovarian cancer using publicly available Next-Gen sequencing data. Network Modeling Analysis in Health Informatics and Bioinformatics, 7(1), 12.
Jain, B., Raj, U., & Varadwaj, P. K. (2018). Drug Target Interplay: A Network-based Analysis of Human Diseases and the Drug Targets. Current Topics in Medicinal Chemistry, 18(13), 1053–1061.
Gupta, S., Gupta, V., Singh, V., & Varadwaj, P. K. (2018). Extrapolation of significant genes and transcriptional regulatory networks involved in Zea mays in response in UV-B stress. Genes & Genomics, 40(9), 973–990.
Das, P. S., Poddar, R., Sarkar, S., Megha, M., Sundararajan, V. S., Nallapeta, S., … others. (2018). Twelve years of BIOinformatics CLUb for Experimenting Scientists (Bioclues). PeerJ Preprints, 6, e26503v1.
Gupta, S., & Varadwaj, P. K. (2018). A BRIEF OVERVIEW ON MOLECULAR DYNAMICS SIMULATION OF BIOMOLECULAR SYSTEM: PROCEDURE, ALGORITHMS AND APPLICATIONS. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 9(4), 1333–1350.
Mishra, S., Aier, I., Varadwaj, P., & Misra, K. (2018). Integrated Pathways of Candida albicans Revealing Potential Targets and Key Factors Accountable for Pathogenicity. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 7(2), 1–10.

Sunil Patel, P. V., Rashmi Tripathi, Vandana Kumari. (2017). DeepInteract: Deep Neural Network Based Protein-Protein Interaction Prediction Tool. Current Bioinformatics, 12(06), 551–557.
Raj U, V. P., Kumar H. (2017). Molecular docking and dynamics simulation study of flavonoids as BET bromodomain inhibitors. J Biomol Struct Dyn., 35(11), 2351–2362.
Prashant Kumar, A. M., Saurabh Gupta, Pritish Varadwaj. (2017). Docking-based screening of Ficus religiosa phytochemicals as inhibitors of human histamine H2 receptor. In 4th International Conference on Emerging Trends in Protein Science & Proteomics,GENOPRO 2017, At Invertis University,Bareilly.
Semwal, R., Aier, I., Raj, U., & Varadwaj, P. K. (2017). Pharmadoop: a tool for pharmacophore searching using Hadoop framework. Network Modeling Analysis in Health Informatics and Bioinformatics, 6(1), 20.
Chaudhary, A., Yadav, B. S., Singh, S., Maurya, P. K., Mishra, A., Srivastva, S., … Mani, A. (2017). Docking-based screening of Ficus religiosa phytochemicals as inhibitors of human histamine h2 receptor. Pharmacognosy Magazine, 13(Suppl 3), S706.
Yadav, G., Rao, R., Raj, U., & Varadwaj, P. K. (2017). Computational modeling and analysis of prominent T-cell epitopes for assisting in designing vaccine of ZIKA virus. J. Appl. Pharm. Sci, 7, 116–122.
Raj, U., Aier, I., Semwal, R., & Varadwaj, P. K. (2017). Identification of novel dysregulated key genes in Breast cancer through high throughput ChIP-Seq data analysis. Scientific Reports, 7(1), 1–11.
Tripathi, R., Chakraborty, P., & Varadwaj, P. K. (2017). Unraveling long non-coding RNAs through analysis of high-throughput RNA-sequencing data. Non-Coding RNA Research, 2(2), 111–118.
Raj, U., Pathak, S., Aier, I., Gupta, S., & Varadwaj, P. K. (2017). IN SILICO FINDING OF THE PUTATIVE DRUG TARGETS FROM HYPOTHETICAL SET OF PROTEINS FOR MYCOBACTERIUM LEPRAE TN. Americas, 33926, 36178.
Gupta, S., Yadav, B. S., Raj, U., Freilich, S., & Varadwaj, P. K. (2017). Transcriptomic analysis of soil grown T. aestivum cv. root to reveal the changes in expression of genes in response to multiple nutrients deficiency. Frontiers in Plant Science, 8, 1025.
Raj, U., & Varadwaj, P. K. (2017). Epigenetics and its role in human cancer. In Translational Bioinformatics and Its Application (pp. 249–267). Springer, Dordrecht.
Kumari, V., Tripathi, R., Patel, S., Raj, U., & Varadwaj, P. K. (2017). DUSR (Distributed Ultrafast Shape Recognition): a Hadoop Based Tool to Identify Similar Shaped Ligand Molecules. IJPER DOI: 10.5530/Ijper.51.1.6, 51(1), 34–42.
Batra, R., Saripalli, G., Mohan, A., Gupta, S., Gill, K. S., Varadwaj, P. K., … Gupta, P. K. (2017). Comparative analysis of AGPase genes and encoded proteins in eight monocots and three dicots with emphasis on wheat. Frontiers in Plant Science, 8, 19.
Gupta, S., Kumari, M., Kumar, H., & Varadwaj, P. K. (2017). Genome-wide analysis of miRNAs and Tasi-RNAs in Zea mays in response to phosphate deficiency. Functional & Integrative Genomics, 17(2–3), 335–351.
Raj, U., Sharma, A. K., Aier, I., & Varadwaj, P. K. (2017). In silico characterization of hypothetical proteins obtained from Mycobacterium tuberculosis H37Rv. Network Modeling Analysis in Health Informatics and Bioinformatics, 6(1), 5.